Antacids such as Tums neutralize acid that is already there, working within minutes but wearing off quickly. H2 blockers such as famotidine reduce how much acid the stomach produces and last longer. PPIs such as omeprazole block the proton pumps at the source and give the strongest acid suppression.
Antacids. They chemically neutralize acid on contact, which makes them the right tool for breakthrough symptoms. They do not reduce acid production, so they are not a long-term control strategy on their own.
PPIs are among the most widely used medications in the world and are effective, but years of daily use has been associated with several potential concerns, so the goal is the lowest effective dose. Do not stop a PPI abruptly. Ask your doctor whether you still need it or could step down.
How severe is my GERD, how long should I take this, can we try stepping down to something less powerful, should I take it daily or only as needed, and does it interact with my other medications.
This article is general information, not medical advice. Talk to your doctor about your own symptoms and treatment.